Scientific Presentations

 

Nanosecond pulsed electric field treatment of tumor cell lines triggers immunogenic cell death (ICD)


Poster Presentation: Society of Immunotherpy of Cancer Annual Scientific Meeting, November 2016

Nano-Pulse Stimulation induced three markers of ICD in three tumor cell lines, providing a possible explanation of why in vivo NPS treatment has shown a vaccine-like effect that inhibits secondary tumor growth after subsequent challenges with tumor cells.

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Nanosecond pulsed electric field treatment of murine melanomas initiates an immune response and inhibits metastasis.


Poster Presentation: Society of Immunotherpy of Cancer Annual Scientific Meeting, November 2016

Mice given a single melanoma tumor which were later either treated surgically or with Nano-Pulse Stimulation treatment. When subsequently challenged with intravenously injected melanoma cells, the NPS-treated mice exhibited fewer metastases than did the mice that had surgical removal, suggesting that the immune system had removed some of the melanoma cells from circulation in the NPS treated mice. This observation extends NPS’s vaccination effect beyond secondary tumor challenge to circulating cancer cells.

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Adaptive immune response to Nano-Pulse Stimulation


Poster Presentation: Society of Immunotherpy of Cancer Annual Scientific Meeting, November 2016

Nano-Pulse Stimulation treated murine fibrosarcoma tumors significantly increased the infiltration of immune system cells into the treated primary tumor and three weeks later challenge tumors were completely rejected due to the production and increase in functionality of T cells.

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